Rethinking biology, with math in tow - Lab Rats

Rethinking biology, with math in tow

Seema Singh - Sunday, August 02, 2009 5:44 PM

For long, biology and math have been somewhat mutually exclusive, at least in this part of the world and in initial years of education. In any case, introducing math to biologists later in career turns out a tad too late or difficult for optimal use.

Now, a large part of the scientific community is rethinking biology education, which apparently needs to undergo mutation, one that is induced by mathematics. Computing Has Transformed Biology -- Biology Education Must Catch Up, is the title of a paper in this week's Science. The authors argue that the recent marriage of advanced computing with biological research - now known as bioinformatics - demands that undergraduate biology curricula be revamped in order to prepare students to use and understand these new tools and concepts.

They say that an additional required course, focused on algorithmic, mathematical, and statistical concepts in biology, should provide biology students with the foundation to understand more complex computation

In another paper, Mathematical Biology Education: Beyond Calculus, two authors suggest that biology students might be getting enough calculus - but not enough algebra. They say algebraic models have many of the features necessary for integrating math and science, though they receive less attention than models based on differential equations or other continuous-time models. They insist that these algebraic models, which in many cases can be simpler to conceive, develop and interpret, should be considered critical for the professional development of the new generation of biologists.

 

(Even if a biologist is missing the math gene, as this cartoon shows, one has little choice if a serious career in biology is to be made ;)

Back home, while there is an interesting debate going on among academics on  biology as a discipline and an enterprise, I am not sure if there is any serious effort at the undergrad level to revamp the curricula, similar to what the US National Science Foundation is doing. The NSF convened a huge gathering of 500 researchers and policy makers in DC last month to chart a course for biology. Their belief: improving introductory biology is a critical step toward raising the nation's scientific literacy.

But what is heartening is to see the department of biotechnology trying to encourage more bio-enterprises. Last week a first-of-its kind contest - BEST 2009-came to a close in Bangalore. It was executed by the Association of Biotech Led Enterprises in which it received over 150 concept notes from various student teams (across the country) to start bio-enterprises, then selected 20 to attend the intensive workshop at Bangalore and picked three teams as winners. More about the winners here.

 

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From Shoba Narayan

August 7, 2009 9:00 PM
Seema: in which science discipline is Math not required? Since I suck at Math, that's what I'd like to know.

From Seema Singh

August 9, 2009 11:52 AM

It is required but if check out how biology is taught, you'd know how math is almost excluded in the formative years. It starts right from +2 levels. How many students keep both bio and math in their 11th and 12th? It often becomes either/ or. The curriculum doesn't facilitate.

From vijey

August 17, 2009 2:04 PM
I am not sure about the other parts of india as far as biology being taught in conjunction with mathemathics but bangalore(karnataka , for that matter) has mathemathics along with biology as an option at the +2 level.but the problem is still the same, in the sense that the application of maths to biology is almost non existent and the two subjects are treated as parallel lines at best.I've done PCMB myself and i have no clue whatsover how to apply mathemathics to biology:D

From Yashaswini

August 17, 2009 2:27 PM
I very much agree with vijey here. Infact not only at the +2 level but the problem persists even at the masters level. Haing done masters in biochemistry, I am still wondering how mathematics can be applied although I know for a fact that it is mathematics and statistics that can facilitate application of biology. As the knowledge is advancing, it has become imperative to merge various fields and encourage interdisciplinary courses. Infact to be good at bioinformatics, as the name suggets one has to be well versed at bio, math and computer science!!!

From Seema Singh

August 18, 2009 12:28 PM
Vijey & Yashaswini: My point is precisely this. Even if institutions do offer PCMB, the way courses are structured or taught, it ensures that students don't understand how modern tools can be used. It's time the conventional bio courses got revamped so that students become multi-disciplinary early on.

From Chetan

August 19, 2009 2:52 PM
Fully agree that the two subjects are taught "at best in parallel". The IISERs may be the first to attempt an integrative biology curriculum at the UG level. The flip side is that engineers and other 'physical science' majors need to be taught some biology as well - the bio-mimetics kind of engineering activities will not be possible otherwise. However there are CSIR institutes like (shameless self-promotion here) NCL and IGIB where there are ongoing research collaborations between 'pure' biologists and engineers using mathematics to analyze biological processes and data. Yashaswini: As a Biochemistry masters graduate, you would have been taught enzyme kinetics or at least steady-state inhibition properties arising from different kinds of inhibitors (competitive, uncompetitive etc). That is math!

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